The chemical synthesis of naturally occurring corticosteroids has led to the generation of artificial corticosteroids that are used in therapeutic veterinary drugs. Many of these drugs are also used as growth promoters particularly in cattle, often in combination with beta-agonists. Dexamethasone, Flumethasone and Betamethasone all belong to this group of drugs that are also known as glucocorticosteriods. The European Union has banned the use of corticosteroids administration for fattening purposes in animals. The Randox Food Diagnostics Corticosteroids ELISA test kit can be used to detect Dexamethasone, Flumethasone and Betamethasone within a urine sample.
Corticosteroids ELISA in Urine (IDM2156)
Assay
|
Compound
|
% Cross reactivity
|
LOD (ppb)
|
Dexamethasone
|
Dexamethasone
|
100
|
(Rapid screen ) 0.25
(IAC) 0.1
|
Dexamethasone 21 Acetate
|
162
|
Dexamethasone 21 Phospate
|
3.6
|
Flumethasone
|
Flumethasone
|
50
|
(Rapid screen ) 5.0
(IAC) 0.2
|
Betamethasone
|
Betamethasone
|
43
|
(Rapid screen ) 5.8
(IAC) 0.23
|
Betamethasone 21 Acetate
|
73
|
Betamethasone 21 Phosphate
|
2.0
|
Triamcionlone
|
1.0
|
Prednisolone
|
1.7
|
Cortisol
|
<0.5
|
Cortisone
|
<0.5
|