Beta-lactam antibiotics are among the most widely used antibiotics for the treatment of bacterial infections in man and animals. Beta-lactams are also administered to animals in feed for growth promotion and for collective prophylactic treatment. The monitoring of beta-lactam residues in edible tissues and milk is important because of the hypersensitivity of some individuals to these antibiotics and also the emergence of antibiotic-resistant strains of bacteria. For this reason, maximum residue limits have been specified for food products and milk to try and control the levels of these antibiotics reaching the consumer.
The Randox Food Diagnostics Beta-lactam ELISA test kit offers antimicrobial testing for beta-lactam antibiotics across a range of food and veterinary matrices.
Beta-lactam ELISA
Assay
|
Compound
|
% Cross-Reactivity
|
LOD (ppb)
|
Beta-lactam
|
Nafcillin
|
144
|
Milk 0.38
Milk powder 0.15
Urine 2.5
Serum 1.5
Tissue 10.0
|
Ampicillin
|
100
|
Amoxicillin
|
94
|
Piperacillin
|
92
|
Azlocillin
|
89
|
Cloxacillin
|
69
|
Penicillin G
|
56
|
Dicloxacillin
|
52
|
Oxacillin
|
51
|
Metampicillin
|
30
|
Penicillin V
|
22
|
Carbenicillin
|
8
|
Ticarcillin
|
6
|
Cephalosporins
|
<0.01
|