Product Code | 1703 |
Bead Size | 60-160um |
Agarose concentration | 4% |
Spacer arm | 10 atoms, hydrophilic |
Flow rate | 500cm/h* |
Cleaning | 0.15M NaOH |
Storage conditions | 20% ethanol, 2-8C |
Functional group to attach | NH2 of small molecule |
Reactive group concentration | 30-35umoles |
Temperature stability range | Ambient |
Functional ligand | COOH |
Blocking agents | Ethanolamine |
Coupling in organic solvents | Yes |
Coupling in a packed column | No |
pH stability range | 2-13 |
Coupling conditions | pH 4-6, at 0-22C for 1-16 hours |
Chemical stability | 0.1M NaOH, 8M urea, 6M guanidine, ethanol and common buffers |
Drug master file | U.S. Food & Drug Administration |
*Flow rate determined in a 1.5x5cm column
-For stable immobilization of small ligands through the primary amine group
-Long space arm facilitates immobilizing peptides
-High flow rates
-High subsititution levels: immobilizations can easily reach 20mg immbolizied protein per ml resin
-Utilizes Sterogene's patented Ultraflow 4 matrix
-Cleanable and industrial process-ready
-cGMP manufacturing; Regulatory Support File available
-DMF with USFDA
Carboxygel effectively couples peptides and small ligands. The medium is recommended primarily for linking small ligands in situations where long hydrophilic spacer arms are needed to allow access of the protein. Carboxygel features a high subsitution level and a high coupling efficiency, and is capable of coupling in both aqueous solutions and organic solvents.